University of Manchester
Galli Lab Publications
The air-breathing Alaska blackfish (Dallia pectoralis) remodels ventricular Ca2+cycling with chronic hypoxic submergence to maintain ventricular contractility
Galli GLJ, Shiels HA, White E, Couturier CS, Stecyk JAW. Comp Biochem Physiol A Mol Integr Physiol. (2023) Feb;276:111355
REVIEW: Effects of Developmental Hypoxia on the Vertebrate Cardiovascular System
Galli GLJ, Lock MC, Smith KLM, Giussani DA and Crossley DA 2nd (2023): Physiology: Mar 1;38(2):0.
Low production of mitochondrial reactive oxygen species after anoxia and reoxygenation in turtle hearts
Bundgaard A, Gruszczyk AV, Prag HA, Williams C, McIntyre A, Ruhr IM, James AM, Galli GLJ, Murphy MP, Fago A (2023): J Exp Biol. 1;226(9)
Chronic developmental hypoxia alters mitochondrial oxidative capacity and reactive oxygen species production in the fetal rat heart in a sex?dependent manner.
Smith, K. L. M., Swiderska, A., Lock, M. C., Graham, L., Iswari, W., et al. & Galli, G. L. J. (2022) Journal of Pineal Research. 73: e12821
The air-breathing Alaska blackfish (Dallia pectoralis) remodels ventricular Ca2+ cycling with chronic hypoxic submergence to maintain ventricular contractility.
Shiels HA, White E, Couturier CS, Hall D, Royal S, Galli GLJ and Stecyk JAW (2022). Curr Res Physiol. 10;5:25-35.
Maternal melatonin: Effective intervention against developmental programming of cardiovascular dysfunction in adult offspring from complicated pregnancy. J. Pineal. Res. 12766.
Hansell A.J., Richter H.G., Camm E.J., Herrera E.A., Blanco C.E., Villamor E., Patey O.V., Lock M.C., Trafford A.W., Galli, G.L.J, Giussani D.A. (2022). J. Pineal. Res. 12766.
The Long-Term Effects of Developmental Hypoxia on Cardiac Mitochondrial Function in Snapping Turtles.
Galli, GLJ., Ruhr, IM, Crossley J, and Crossley, DA (2021). Frontiers in Physiology. 12
Developmental programming of DNA methylation and gene expression patterns is associated with extreme cardiovascular tolerance to anoxia in the common snapping turtle.
Ruhr IM, Bierstedt J, Rhen T, Das D, Singh SK, Miller S, Crossley DA and Galli GLJ (2021). Epigenetics and chromatin, 14: 42
Draft Genome of the Common Snapping Turtle, Chelydra serpentina, a Model for Phenotypic Plasticity in Reptiles
Das, D, Kumar Singh, S, Bierstedt, J, Erickson, A, Galli, G, Crossley, D Rhen, T (2020). Volume 10, Issue 12, 4299�4314;
REVIEW: Novel Therapeutic Targets for Hypoxia-Related Cardiovascular Diseases: The Role of HIF-1.
Liu, M, Galli, G, Wang, Y, Fan, Q, Wang, Z, Wang, X and Xiao, W (2020). Frontiers in Physiology, 11: 774.
Sex-dependent effects of developmental hypoxia on adult offspring cardiac mitochondria.
Hellgren, KT, Premanandham H, Quinn CJ, Trafford AW and Galli GLJ (2020): Free Radical Biology and Medicine. 162:490-499.
Gill filament permeabilization: A novel approach to assess mitochondrial function in sheepshead minnows (Cyprinodon variegatus) following anthraquinone exposure.
Reynolds Kirby A, Galli G, Crossley J, Sweet L, Crossley DAII and Roberts A (2020). Comp. Biochem. Physiol. C: 230, 108699
Cardiac Mitochondrial Function Depends on BUD23 Mediated Ribosome Programming.
Baxter M, Voronkov M, Poolman T, Galli GLJ, Pinali C (et. al) Ray D (2020): Elife Jan 15;9:e50705.
Prolonged phenanthrene exposure reduces cardiac function but fails to mount a significant oxidative stress response in the signal crayfish (Pacifastacus leniusculus).
Ainerua MO, Tinwell J, Murphy R, Galli GLJ, Van Dongen BE, White KN and Shiels HA (2020): Apr:268:129297
Developmental plasticity of cardiac anoxia-tolerance in juvenile common snapping turtles (Chelydra serpentina).
Ruhr I.M., McCourty H, Bajjig A, Crossley DA, Shiels HA, Galli GLJ (2019). Proceedings Royal Society B: 26;286(1905):20191072.
Metabolic adaptations to anoxia and reoxygenation: New lessons from freshwater turtles and crucian carp.
Bundgaard, A., Ruhr, I., Fago, A. and Galli, GLJ (2020). Curr Opin Endo Met Res 11, 55-64
Impacts of deepwater horizon crude oil on mahi-mahi (coryphaena hippurus) heart cell function.
Heuer RM, Galli GLJ, Shiels HA, Fieber LA, Cox GK, Mager EM, Stieglitz JD, Benetti DD, Grosell M, Crossley Ii DA (2019). Environ Sci Technol. 20;53(16):9895-9904.
Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking. Nature Communications 28;10(1):2889
Linscheid N, Logantha SJRJ, Poulsen PC, Zhang S, Schr�lkamp M, Egerod KL, Thompson JJ, Kitmitto A, Galli G, Humphries MJ, Zhang H, Pers TH, Olsen JV, Boyett M, Lundby A (2019). Nature Communications 28;10(1):2889.
A Novel Cardiotoxic Mechanism for a pervasive global pollutant.
Brette, F., Shiels, H., Galli, G.L.J., Cros, C., Incardona, J., Scholz, N. & Block, B. A (2017): Nature Scientific Reports: 7: 41476.
Metabolic stress-induced cardiomyopathy is caused by mitochondrial dysfunction due to attenuated Erk5 signalling.
Liu, W., Ruiz Velasco Hernandez, A., Wang, S., Khan, S., Zi, M., Jungmann, A., Camacho-Munoz, M. D., Guo, J., Du, G., Xie, L., Oceandy, D., Nicolaou, A., Galli, G., M�ller, O. J., Cartwright, E., Ji, Y. & Wang, X. (2017): Nature Communications: 8:494.
Ginkgolide K protects the heart against ER stress injury by activating the IRE1?/XBP1 pathway.
Wang, S, Wang, Z, Fan, Q, Guo, J, Galli, GLJ, Du, G, Wang, X and Xiao, W (2016): Br. J. Pharm. 173(15):2402-18.
The effects of smoking on whisker movements: A quantitative measure of exploratory behavior in rodents
Grant, RA, Cielen, N, Maes, K, Heulens, N, Galli, GLJ, Janssens, W, Gayan-Ramirez, G, Degens, H (2016): Behav. Process. 128: 17�23
Developmental Plasticity of Mitochondrial Function in American Alligators, Alligator mississippiensis.
Galli, G.L.J., Crossley, J., Elsey, R. M., Dzialowski, E. M., Shiels, H. & Crossley , D. A. (2016): Am. J. Physiol: 311: R1164-R1172
Cardiac function in an endothermic fish: Cellular mechanisms for overcoming acute thermal challenges during diving.
Shiels HA, Galli GLJ, Block BA. (2015): Proceedings Royal Society B: 2015 7: 282
REVIEW: Mitochondria from anoxia-tolerant animals reveal common strategies to survive without O2.
Galli GLJ, Lau G and Richards JG (2014): J Com. Physiol.184:285
Direct measurements of SR free Ca reveal the mechanism underlying the transient effects of RyR potentiation under physiological conditions
Greensmith DJ, Galli GLJ, Trafford AW, Eisner DA (2014): Cardiov. Res. 103:554-63.
REVIEW: The sarcoplasmic reticulum and the evolution of the vertebrate heart.
Shiels, HA and Galli GLJ (2014): Physiology 29: 456-469
Beating Oxygen: Chronic anoxia exposure reduces mitochondrial F1FO-ATPase activity in turtle (Trachemys scripta) heart
Galli GLJ, Lau G and Richards JG (2013): J. Exp.Biol. 216:3283-93
The effect of temperature on mitochondrial respiration in permeabilized cardiac fibres from the freshwater turtle, Trachemys scripta
Galli, GLJ and Richards, JG (2012): J. Therm Biol. 37: 195�200
Temperature effects on Ca2+ cycling in scombrid cardiomyocytes: A phylogenetic comparison.
Galli GLJ, Lipnick, MS, Shiels HA and Block BA (2011): J. Exp. Biol. 214:1068-76.
Hypercapnic acidosis and sarcoplasmic reticulum function in the ventricle of the armoured catfish, Liposarcus pardalis.
Shiels HA, Santiago DA and Galli GLJ (2010): Physiol. Biochem. Zool. 83: 366-75
The cellular force-frequency response in ventricular myocytes from the varanid lizard, Varanus exanthematicus.
Warren DE, Galli GLJ, Patrick SM, Shiels HA (2010): Am. J. Physiol. 298:R567-74.
Temperature Sensitivity of Cardiac Function in Pelagic Fishes with Different Vertical Mobilities: Yellowfin Tuna (Thunnus albacares), Bigeye Tuna (Thunnus obesus), Mahimahi (Coryphaena hippurus), and Swordfish (Xiphias gladius)
Galli GLJ, Shiels HA and Brill R (2009).
The effect of thermal acclimation on action potentials and sarcolemmal K+ channels from Pacific bluefin tuna cardiomyocytes
Galli GLJ, Lipnick M and Block B (2009).
Ca2+ cycling in cardiomyocytes from a high performance reptile, the varanid lizard, Varanus Exanthematicus.
Galli GLJ, Warren D and Shiels HA (2009): Am. J. Physiol. 297: R1636-44
REVIEW: Cardiac survival in anoxia-tolerant vertebrates: an electrophysiological perspective.
Stecyk JAW, Galli GLJ, Shiels HA and Farrell AP (2008): Comp. Biochem. Physiol. C 148(4): 339-54.
Adrenergic regulation of the cardiovascular system in the South American rattlesnake, Crotalus durissus.
Galli GLJ, Skovgaard N, Abe A, Taylor EW and Wang T (2007).
Calcium flux in turtle ventricular myocytes.
Galli GLJ, Taylor EW and Shiels HA (2006): Am. J. Physiol. 291: R1781-R1789
The role of the sarcoplasmic reticulum in the generation of high heart rates and blood pressures in reptiles.
Galli GLJ, Gesser H, Taylor EW, Shiels HA and Wang T (2006).
Cardiovascular actions of rattlesnake bradykinin ([Val1,Thr6]bradykinin) in the anesthetized South American rattlesnake Crotalus durissus terrificus
Galli GLJ, Skovgaard N, Taylor EW, Abe AS, Conlon JM and Wang T (2005). Am. J. Physiol. 288: R456-65
Hemodynamic effects of python neuropeptide gamma in the anesthetized python, Python regius.
Skovgaard N, Galli GLJ, Taylor EW, Conlon JM and Wang T (2005): Reg. Pep. 128: 15-26.
The role of nitric oxide in the regulation of the systemic and pulmonary vasculature of the rattlesnake, Crotalus durissus terrificus (Crotalus durissus).
Galli GLJ, Skovgaard N, Taylor EW, Abe AS, Conlon JM and Wang T (2005).: J. Comp. Physiol. B, 175: 201-208
The role of nitric oxide in regulation of the cardiovascular system in reptiles.
Skovgaard N, Galli GLJ, Abe A, Taylor EW and Wang T. (2005): Comp. Biochem. Physiol. 142: 205-14
The cardiovascular responses of the freshwater turtle, Trachemys scripta, to warming and cooling.
Galli GLJ, Taylor EW and Wang T (2004): J. Exp. Biol. 207: 1471-1478